Biologists and cardiologists from UT Southwestern teamed up to conduct a tissue study in mice to learn about the regeneration of the heart tissues. They found out that the very small micro RNAs strands were responsible for the regulation of gene expression that subsequently contributes to the regeneration ability of the heart about a week after birth. Immediately, after this, the regeneration ability of the heart goes completely.

Through determination of the crucial mechanism that guides the regenerative on and off functions of the heart, these researchers are beginning to get a better understanding the heart’s regeneration ability resulting from an injury resulting from a cardiovascular surgery. This has been the number one hurdle in the cardiovascular researches for a long time.

The findings of the research will usher in end of heart disease fatalities

The researchers believe that since they started studying the response of the heart tissue cells to a heart attack. This procedure is the only one that can induce possible activation of endogenous regeneration programs. This is according to leading researchers of the breakthrough findings who have worked for hours on end in the cardiology division of internal medicine.

According to cardiovascular studies conducted from medical databases, about a million individuals in the United States experience a heart attack, while more than fifty percent of them succumb to the heart disorder every year. Again, according to the SDCP (Society for Disease Control and Prevention) figures, the heart infection and related complications are the leading causes of loss of life in women and men, especially those advanced in age.

Researchers in the world are concentrating on studies to break through myriad conditions and injuries associated with the human heart. The UT Southwest scientists are focused on finding out more about the regenerative ability of the heart. A research spearheaded by leaders of the Molecular Biology indicated that in a span of precisely weeks after removing about fifteen percent of the heart of a mouse, the heart regenerated the lost sections and assumed the normal appearance and functionality.

Latest investigations demonstrated the thorough regenerative capability of the heart of a young rodent after myocardial infractions. However, the researchers found out that the regenerative activity lasts for one week of life after which it is disabled by a certain micro-RNA referred to as MiR-15. The investigation also found out that blocking of MiR-15 would cause the sustainment of the regenerative process for a longer period.

Research is good news for other research projects

The UTSW research has been referred to as ‘a fresh perspective on an aged problem’ by researchers of other cardiovascular research institutes. The research has provided encouragement to other researchers since its initial findings provide the investigators with therapeutic opportunities for the manipulation of the regenerative capabilities of the heart.

The research is seen as a new era in the biology of heart tissue cells regeneration in mammalian hearts, but more research is still needed for optimizing the way clinicians, and cardiac specialists put the process under control.