The link between intake of fluids and kidney maladiesAutosomal dominant interstitial kidney disease is a rare collection of diseases affecting the known functions of the kidney. In simple terms, the condition is characterized by: one develops a kidney disease and undergoes a kidney transplant and other diseases associated with acidic concentration in the blood and gout. In theory, the condition will occur even if the genetic change is inherited from one parent and sporadically occurs when there is no family history.

Common names of autosomal dominant interstitial kidney disease

The condition has other names as well namely: medullary cystic kidney disease, although this name is not used as much because most people suffering from this condition do not have medullary cysts. It is also referred to as juvenile hyperuricemic nephropathy. The disease tends to affect people of ages 20 to 50. The latter condition as aforementioned occurs in young children, something, which translate to get it from both parents.
Cystic kidney disease is an inherited condition whereby the cysts in the centre of each kidney gradually lose their ability to function properly. Cysts refer to abnormal blisters of fluid in the kidney. The condition further scares the kidney making unable to concentrate the urine and as a result, producing too much urine. Its symptoms include excessive urination, salt cravings, weakness, confusion, bleeding, fatigue, frequent hiccups, low blood pressure, nausea and vomiting, headaches, pale skin, reduced sensation in the hands, weight loss among many others. Other complications include: anemia, ulcers, loss of bone density, infertility and other heart related problems.
Its analysis incorporates blood tests to check for sodium levels and general kidney functions, urine tests to check the levels of concentration and other imbalances, x rays to check for the size of kidneys that may be altered owing to increased urine concentrations, renal biopsy and genetic testing to verify any genetic changes that might have taken place in due time.
While the disease does not have a cut and dry treatment to it, one may focus on controlling measures, which include intake of fluids and salt to supplement the one lost as the disease progresses into latter stages. This also helps reduce dehydration. Other treatments include taking of prescribed medication and diet changes and minimal intakes of foods containing phosphorous and potassium. Further complications may also require one to have a kidney transplant. Basically, this is not a curable disease but rather a manageable once detected in the early stages.

The common yet different factor of Autosomal dominant interstitial kidney disease

Nephronophthisis and medullary cystic kidney disease are mainly grouped together because, in essence, they share the same features but with a slight difference in regards inheritance patterns to the former affecting children and the latter affecting young adults and older age groups. Similar features for both are ADH resistant urine concentration that leads to polyuria and polydipsia, anemia and renal diseases.
The former aforementioned condition is Autosomal recessive accounting to 15% of chronic diseases and causes ESRD during early childhood while the latter is Autosomal dominant with a few sporadic new mutations and causes ESRD for people between the ages of 30 and 50.